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Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes

Received: 7 May 2021     Accepted: 25 May 2021     Published: 31 May 2021
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Abstract

The experiment goal was the investigation of thyme (T), celery (C) and salinomycin effects on immune response, neurotransmitters related to milk production in Barki ewes. Total 72 mature ewes (2-3 years & 40±1.5 Kg BW) randomly pined equally into five groups. Group-1 was control; groups 2 & 3 received 20g/head/day T and C, respectively. Group-4 received 10g T+ 10g C/head/day, group-5 treated with salinomycin 1g/head/day. Samples collected during 2nd, 3rd trimester of pregnancy and on delivery day (DD); milk yield assessed on 15, 30 and 45-day postpartum. T and/or C and salinomycin increased (P<0.05) superoxide dismutase (SOD), reduced glutathione (GSH) and glutathione disulfide (GSSG) during mid-, late-pregnancy and DD compared to control, celery and thyme increase malondialdehyde (MDA) (p<0.05) during mid-and late-pregnancy, respectively compared to other groups. Nitric oxide (NO) levels increased in thyme X celery (TxC) group during mid-pregnancy and DD with insignificantly compared with other groups. During mid-pregnancy TxC treatment increased (p<0.05) serotonin (5-HT) levels compared with other groups, the same was dopamine (DA), norepinephrine (NE) and tryptophan (Trp) levels (P>0.05). During late pregnancy 5-HT, DA, NE & Trp increased (P<0.05) in the thyme and/or celery group. While on DD salinomycin increased neurotransmitters (P<0.05) with an insignificant increase in other groups. Milk yield increased (P<0.05) during 15, 30 and 45 days postpartum in T and/or C groups than control and salinomycin. In conclusion, the applied treatments had a significant effect on reproductive performance, immune response in ewes throughout pregnancy and DD periods, and milk production during the postpartum period.

Published in Advances in Applied Physiology (Volume 6, Issue 1)
DOI 10.11648/j.aap.20210601.14
Page(s) 23-29
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Thyme, Celery, Salinomycin, Immune System, Neurotransmitters, Milk Yield, Ewes

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    Sherif Yousif Eid, Omar Abdel Hamid Ahmed-Farid, Hussein Mostafa El-Zaher, Mahmoud Mohammed Shabaan. (2021). Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes. Advances in Applied Physiology, 6(1), 23-29. https://doi.org/10.11648/j.aap.20210601.14

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    ACS Style

    Sherif Yousif Eid; Omar Abdel Hamid Ahmed-Farid; Hussein Mostafa El-Zaher; Mahmoud Mohammed Shabaan. Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes. Adv. Appl. Physiol. 2021, 6(1), 23-29. doi: 10.11648/j.aap.20210601.14

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    AMA Style

    Sherif Yousif Eid, Omar Abdel Hamid Ahmed-Farid, Hussein Mostafa El-Zaher, Mahmoud Mohammed Shabaan. Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes. Adv Appl Physiol. 2021;6(1):23-29. doi: 10.11648/j.aap.20210601.14

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  • @article{10.11648/j.aap.20210601.14,
      author = {Sherif Yousif Eid and Omar Abdel Hamid Ahmed-Farid and Hussein Mostafa El-Zaher and Mahmoud Mohammed Shabaan},
      title = {Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes},
      journal = {Advances in Applied Physiology},
      volume = {6},
      number = {1},
      pages = {23-29},
      doi = {10.11648/j.aap.20210601.14},
      url = {https://doi.org/10.11648/j.aap.20210601.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.aap.20210601.14},
      abstract = {The experiment goal was the investigation of thyme (T), celery (C) and salinomycin effects on immune response, neurotransmitters related to milk production in Barki ewes. Total 72 mature ewes (2-3 years & 40±1.5 Kg BW) randomly pined equally into five groups. Group-1 was control; groups 2 & 3 received 20g/head/day T and C, respectively. Group-4 received 10g T+ 10g C/head/day, group-5 treated with salinomycin 1g/head/day. Samples collected during 2nd, 3rd trimester of pregnancy and on delivery day (DD); milk yield assessed on 15, 30 and 45-day postpartum. T and/or C and salinomycin increased (P0.05). During late pregnancy 5-HT, DA, NE & Trp increased (P<0.05) in the thyme and/or celery group. While on DD salinomycin increased neurotransmitters (P<0.05) with an insignificant increase in other groups. Milk yield increased (P<0.05) during 15, 30 and 45 days postpartum in T and/or C groups than control and salinomycin. In conclusion, the applied treatments had a significant effect on reproductive performance, immune response in ewes throughout pregnancy and DD periods, and milk production during the postpartum period.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - Thyme, Celery and Salinomycin Implication on Antioxidant Capacity and Neurotransmitters Related to Milk Production in Pregnant Barki Ewes
    AU  - Sherif Yousif Eid
    AU  - Omar Abdel Hamid Ahmed-Farid
    AU  - Hussein Mostafa El-Zaher
    AU  - Mahmoud Mohammed Shabaan
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    N1  - https://doi.org/10.11648/j.aap.20210601.14
    DO  - 10.11648/j.aap.20210601.14
    T2  - Advances in Applied Physiology
    JF  - Advances in Applied Physiology
    JO  - Advances in Applied Physiology
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    EP  - 29
    PB  - Science Publishing Group
    SN  - 2471-9714
    UR  - https://doi.org/10.11648/j.aap.20210601.14
    AB  - The experiment goal was the investigation of thyme (T), celery (C) and salinomycin effects on immune response, neurotransmitters related to milk production in Barki ewes. Total 72 mature ewes (2-3 years & 40±1.5 Kg BW) randomly pined equally into five groups. Group-1 was control; groups 2 & 3 received 20g/head/day T and C, respectively. Group-4 received 10g T+ 10g C/head/day, group-5 treated with salinomycin 1g/head/day. Samples collected during 2nd, 3rd trimester of pregnancy and on delivery day (DD); milk yield assessed on 15, 30 and 45-day postpartum. T and/or C and salinomycin increased (P0.05). During late pregnancy 5-HT, DA, NE & Trp increased (P<0.05) in the thyme and/or celery group. While on DD salinomycin increased neurotransmitters (P<0.05) with an insignificant increase in other groups. Milk yield increased (P<0.05) during 15, 30 and 45 days postpartum in T and/or C groups than control and salinomycin. In conclusion, the applied treatments had a significant effect on reproductive performance, immune response in ewes throughout pregnancy and DD periods, and milk production during the postpartum period.
    VL  - 6
    IS  - 1
    ER  - 

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Author Information
  • Biological Applications Department, Egyptian Atomic Energy Authority (EAEA), Cairo, Egypt

  • Physiology Department, National Organization for Drug Control and Research (NODCAR), Cairo, Egypt

  • Biological Applications Department, Egyptian Atomic Energy Authority (EAEA), Cairo, Egypt

  • Biological Applications Department, Egyptian Atomic Energy Authority (EAEA), Cairo, Egypt

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